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Streptozocin链脲佐菌素,STZ
产品编号 S0130 | CAS18883-66-4 | Sigma
Streptozocin 链脲佐菌素, STZ
75% α -anomer basis, 98% (HPLC), powder

 

 
货号与规格 库存   价格 (RMB) 数量

S0130-100MG

 

国内现货

 

589.68

260.00

S0130-500MG

 

国内现货

 

1,462.50

550.00

S0130-1G

 

国内现货

 

2,351.70

960.00

☆ 购买1G包装送100元充值卡/订购500mg送小米移动电源

 

产品描述

Frequently Asked Questions

Live Chat and  Frequently Asked Questions  are available for this Product.

Application

Streptozocin is used to induce Type 1 diabetes for medical research.

General description

Streptozotocin, a glucosamine-nitrosourea, is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Streptozocin, a diabetagen, is especially toxic to pancreatic islet insulin-producing β-cells. It is toxic to GLUT2 positive neuroendocrine tumor cells.

Other Notes

Mixed anomers

包装

1, 5 g in glass bottle

100, 500 mg in glass bottle

50 mg in poly bottle

Biochem/physiol Actions

An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets; induces death of insulin-secreting cells, producing an animal model of diabetes. Potent DNA methylating agent that induces chromosomal breakage.1  Cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.

性质

Related Categories Antibiotics,  Antibiotics A to Z,  Antibiotics N-S,Antibiotics by Application,  Antineoplastic and Immunosuppressive Antibiotics,
assay   ≥75% α-anomer basis
  ≥98% (HPLC)
form   powder
color   white to off-white
mp   121 °C (dec.)(lit.)
storage temp.   −20°C
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